Alzheimer's

"Productively is the way to age," says Ruth Finkelstein, associate director of Columbia’s Robert N. Butler Aging Center. She discusses the center's interdisciplinary approach to studying aging and the implications of longer lifespans on society.

In the movie Still Alice, Julianne Moore plays a Columbia linguistics professor who is diagnosed with early-onset Alzheimer’s, an extremely rare version of the disease.

Research at Columbia

NEW YORK, NY (April 20, 2014) — A team of researchers from Columbia University Medical Center (CUMC), Weill Cornell Medical College, and Brandeis University has devised a wholly new approach to the treatment of Alzheimer’s disease involving the so-called retromer protein complex.

Neuroscience at Columbia

Using high-resolution functional MRI (fMRI) imaging in patients with Alzheimer’s disease and in mouse models of the disease, Columbia University Medical Center (CUMC) researchers have clarified three fundamental issues about Alzheimer’s: where it starts, why it starts there, and how it spr

The researchers have identified a protein—RbAp48—that, when increased in aged wild-type mice, improves memory back to that of young wild-type mice. In the image, yellow shows the increased RbAp48 in the dentate gyrus. Image credit: Elias Pavlopoulos, PhD/Columbia University Medical Cente

Study points to possible treatments and confirms distinction between memory loss due to aging and that of Alzheimer's

Research at Columbia

African-Americans with a variant of the ABCA7 gene have almost double the risk of developing late-onset Alzheimer’s disease compared with African-Americans who lack the variant.