Neuroscience

School students arrived at the New York State Psychiatric Institute’s Kolb Annex on the Columbia University Medical Center campus March 12 to participate in the annual Community Brain Expo, cosponsored by the Mortimer B. Zuckerman Mind Brain Behavior Institute at Columbia University.

Ask Thomas Jessell why he has dedicated his career to understanding the neurobiology of movement, and he puts it in simple terms: “Movement is the overt expression of all behaviors—without movement, intent and desire can be planned and felt but never realized.” Whether it’s the pumping hea

Ask Thomas Jessell why he has dedicated his career to understanding the neurobiology of movement, and he puts it in simple terms: “Movement is the overt expression of all behaviors—without movement, intent and desire can be planned and felt but never realized.” Whether it’s the pumping hea

The Mortimer B. Zuckerman Mind Brain Behavior Institute has named David M. Greenberg as its first executive director. The Zuckerman Institute was established in 2012 with a $200 million gift from New York philanthropist and business leader Mortimer B. Zuckerman.

A modern Muybridge? Singer and composer, Mari Romarheim Haugen illustrates basic steps of the samba, while her movements are captured by an infrared camera.

When Mariusz Kozak was a professional violinist playing with orchestras and chamber ensembles, he noticed how music altered the awareness of time for himself, his fellow musicians and even the audience. Several years later, as he wrote his Ph.D.

New details about how motor neurons die in ALS have been uncovered by a new cell-culture system that combines spinal cord or brain cells from ALS patients with human motor neurons. The culture system shows that patient astrocytes (shown here with a blue-stained nucleus) release a toxin that kills motor neurons via a recently discovered process described as a “controlled cellular explosion.” Image: Diane Re.

In most cases of amyotrophic lateral sclerosis (ALS), or Lou Gehrig’s disease, a toxin released by cells that normally nurture neurons in the brain and spinal cord can trigger loss of the nerve cells affected in the disease, Columbia researchers reported today in the online edition of the

Cortical responses to speech sounds
—Image courtesy of UCSF

Nima Mesgarani, assistant professor of electrical engineering, is the lead author of a new study on how speech sounds are identified by the human brain, offering an unprecedented insight into the basis of human language.

The Vilcek Foundation named Thomas M. Jessell as the winner of the 2014 Vilcek Prize in Biomedical Science. Awarded annually, the prizes honor the contributions of immigrants to the American arts and sciences, and include $100,000 cash awards. Dr.

Neuroscience at Columbia

Using high-resolution functional MRI (fMRI) imaging in patients with Alzheimer’s disease and in mouse models of the disease, Columbia University Medical Center (CUMC) researchers have clarified three fundamental issues about Alzheimer’s: where it starts, why it starts there, and how it spr

An image of newly synthesized proteins in live hippocampal neurons.

In the search to understand memory, Wei Min is looking at cells at the most basic level, long before the formation of neurons and synapses. The assistant professor of chemistry studies the synthesis of proteins, the building blocks of the body formed using genetic code from DNA.

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