Precision Medicine

Lee Goldman Columbia University Prescription for a Healthy Life

Some of the same key survival traits that have kept us alive for thousands of generations are killing us today.

Wendy Chung Genetics Medicine Columbia University

Wendy Chung started medical school the same year that the daunting project of sequencing the human genome began.

Revolutionizing “human-on-a-chip” technology by providing predictive cardiac physiology.

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CUMC patient b2 deficiency
Doctors suspected a young patient had an autoimmune disorder, but genetic testing found a severe vitamin deficiency. Within weeks of treatment with a supplement, her symptoms began to improve.

A 20-month-old girl suffering from a rare neurodegenerative disease was diagnosed by exome sequencing and successfully treated.

Stephen Emerson entered Haverford College with the aim of becoming an astronomer-mathematician. That is, until he met Ariel Loewy, a biology professor on the faculty who encouraged him to change his focus.

One of the world’s largest supercomputers in cancer research, based at CUMC, identified FOXM1 and CENPF as a synergistic driver pair in aggressive prostate cancer. Photo: Lynn Saville.

NEW YORK, NY (May 12, 2014) — Two genes work together to drive the most lethal forms of prostate cancer, according to new research from the Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center (CUMC).

DNA curtains—devised by P&S professor Eric Greene—provide a new way to study DNA-protein interactions. DNA strands are green; proteins are pink. Image: Eric Greene.

Using a dazzling technology to watch proteins collide, clutch, and slide along strands of DNA, researchers at Columbia University College of Physicians & Surgeons and UC-Berkeley report online in Nature that they have uncovered some of the secrets behind a powerful new genetic engineer

For the first time, scientists have succeeded in transforming human stem cells into functional lung and airway cells.

A large, multi-center clinical trial led by researchers from Columbia University Medical Center (CUMC) shows that a new genetic test resulted in significantly more clinically relevant information than the current standard method of prenatal testing.