Synthesizing Superatoms and Finding Success in Science

Columbia chemistry postdoc Elena Meirzadeh shares what’s so special about superatoms and her path through science so far.

Ellen Neff
January 04, 2023

Researchers involved with Columbia’s National Science Foundation-funded Materials Research Science and Engineering Center are hard at work creating and studying new materials with potential applications in quantum technologies, optoelectronics, and energy transport. The latest creation from the labs of chemists Xavier Roy and Colin Nuckolls is graphullerene, a superatomic form of carbon synthesized for the first time in a recent article in Nature

Leading the charge on this new material was Elena Meirzadeh, a postdoc who joined Columbia from Israel's Weizmann Institute in 2018 to learn the secrets of synthetic chemistry with the Roy and Nuckolls labs. Meirzadeh shared her thoughts with Columbia News about molecules, superatoms, and the importance of mentorship as she continues her career as a woman in science. 

Where did your interest in science originate?

I was born and spent my childhood in Tehran, before moving to Jerusalem when I was 12. My dad was an electrical engineer, but I didn’t really meet a lot of scientists growing up. My mom thought I should become a dentist; I originally wanted to be an architect, but I felt like I was really bad at drawing and handwriting things—little did I know everything would soon be electronic! 

Really though, everything seemed interesting and I struggled to find a focus. But I had these conversations with my uncle about weird inventions and startups doing things like making televisions you could smell or self-cleaning fabrics—things that would change people’s lives. 

I realized these were applications of nanotechnology, and I decided that’s what I wanted to pursue. But then I had to figure out how. I knew I needed a science degree, but I thought physics would be too hard and that biology had too many things to memorize. I landed on chemistry, with special thanks to my high school chemistry teacher, who first showed me what went into real experiments.

What was your path to your PhD?

After high school I enrolled at Hebrew University. I planned to get my undergraduate degree and go straight to industry but during my second year, I heard about a summer science program at the Weizmann Institute of Science. It was a two-week program that came with a little scholarship. I had worked all summer to pay for school, so it was like a little paid vacation. I ended up having the best time, and I decided that I wanted to pursue a PhD there.

The problem was, I wasn’t great at school. I hated sitting still all day. I managed to improve my grades and interviewed, but I wasn't accepted. At least initially. So I got another letter of recommendation and decided to write to the dean directly to ask for another chance, and that was that: I got in.

I didn’t feel like I fit in at first, but I had two amazing advisors who did everything in their power to convince me otherwise. One was a chemist, the other an engineer, and they exposed me to really different ways to approach science and ask scientific questions. It was nice to see a balance—asking fundamental scientific questions is great, but you don’t want to be too in the clouds and detached from the potential applications of your work. 

What did you study, and how did that lead you to Columbia?

My thesis was titled, “The Beauty of Imperfections in Molecular Crystals.” Basically, I studied defects in materials and how those imperfections affected their properties. For example, silicon needs intentional defects—introduced via a process called doping—in order for it to be a good transistor in our electronic devices. I also studied how polar crystals affect the freezing temperature of water, which has implications for areas like agriculture, satellites, and airplanes. By using advanced detection technologies, we can get really detailed structural information about a material, which can then help us understand and improve it for whatever purpose you may have in mind.

I did a lot of crystal characterization during grad school, but I really wanted to learn advanced synthesis techniques to make new materials. That’s something that Columbia does really well. I saw one of Xavier Roy’s papers about these unique crystals made from superatoms and they looked like a lot of fun to work with!

So what is a superatom? 

Superatoms are large molecules made from many atoms. Other kinds of molecules will have properties that vary in different areas, but superatoms act as a single unit—in a way, like one huge atom. But their properties can also differ from their constituent elements.

The new form of carbon that we made, graphullerene, consists of superatomic building blocks, but it is also layered. That’s exciting because you can peel the crystals into incredibly thin, 2D sheets, which isn’t possible with other kinds of molecular crystals. In 2D materials, you can explore quantum properties, like electrical transport, magnetism, and superconductivity, and study what happens at the 2D limit or when you combine different atomic layers in different ways. 

It’s an exciting research area that lots of our chemistry, physics, and engineering collaborators at Columbia and beyond are interested in, and I’m excited to synthesize new materials for them to study.

What has been a challenge as a postdoc, and how did you overcome it?

Starting over. By the end of your PhD you feel like you know what you are doing, and you forget what it feels like when things don’t work. My first projects when I got to Columbia just did not work, and that was hard. But there was something Mike Steigerwald, a research scientist here, told me that I try to keep in mind: unless 85 percent of what you are doing is failing, you aren’t doing anything interesting. 

You give a lot of credit to your mentors—how have you tried to pay that forward? 

I was very lucky to have amazing mentors all along the way. They taught me how to keep my antennas up and be open-minded toward unexpected results. They’ve also shown me how to be a scientist, and I want to do that for others. 

Obviously, science is a time-consuming career. At the beginning of graduate school, many of us questioned whether it was possible to “have it all.” So I helped start the Weizmann Women in Chemistry Forum to host seminars and workshops with scientists from both academia and industry and hear about their journeys. We even held an international conference to bring brilliant female chemists from different disciplines together—that was an amazing experience, and we built a really strong network. Weizmann Women in Science also hosted “soft” skills workshops like how to give a scientific talk; how to balance your career; negotiation techniques and time management. After, we would hold student groups to pass on what we learned. 

I was recently invited back as a workshop speaker. It was during COVID and over Zoom, but it was nice to have helped start something that continued on after I graduated. This year, they selected me for one of the inaugural Women’s Postdoctoral Career Development Awards, to further support my career development. 

My real passion has become educating younger students to pursue science, with outreach activities like March Madness and Girl Science Day each year. Maybe my science won’t change the world, but mentoring is one way I know I can really contribute. 

You’ll be moving on from Columbia soon—what are you taking with you? 

Besides a lot of synthetic chemistry skills, I learned a lot about collaborations. One thing I’ve loved here is how people from different labs and departments communicate and work so closely with each other. I think you do much better science that way than by yourself. 

Speaking of communication, do you have any tips for others learning English?

When I started graduate school I barely spoke English, so I started recording myself. I’d listen to how I was pronouncing a word and compare how Google Translate pronounced it. 

I also love slang, and I encourage people to correct me—I want to learn!